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1 Standardized mean differences of covariates in incident GLP-1RA compared to sulfonylureas, DPP4i, SGLT2i, a control composited of equal proportion of incident sulfonylureas, DPP4i, SGLT2i use and a control of participants who received usual care before and after weighting

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Dihexa is not currently regulated or banned by major doping agencies like WADA, but its novel mechanism and unapproved status underscore the need for careful clinical evaluation before widespread use

Severe kidney disease, where dosing should be monitored because the kidneys clear excess B12

The 1x CYP substrate cocktail contained phenacetin (10 M), bupropion (10 M), mephenytoin (50 M), diclofenac (10 M), bufuralol (10 M) and midazolam (5 M)