During viral infections, IFN-I promotes the clearance of the virus, but it may also cause immunosuppression during chronic infections ( 3 cGAS-STING signaling in the progression of RA 3.1 Elevated levels of cfDNA, cGAS, and STING in RA There was a study that systematically reviewed the level and origin of cfDNA in RA ( In vitro , RA synovial fluid enhanced the production of NETs by neutrophils, as evidenced by the increased levels of DNA in culture supernatants and extracellular DNA on NETs ( Compared with the osteoarthritis (OA) patient-derived FLSs, the levels of cGAS mRNA and cGAS protein were higher in RA-FLSs
J Biol Chem 193:265275 Magina KN, Pregartner G, Zebisch A et al (2017) Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis
doi:10.3390/nu11030557
Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls
1 Hyperuricemia increases the risk of not only gout, but other diseases as well, including hypertension , kidney disease , and metabolic syndrome
