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Why Peptides Are Hard to Deliver Orally Peptides are generally vulnerable to proteolytic activity

It reduces pro-inflammatory cytokines like TNF and IL6 while enhancing structural repair

Also, some medical providers are more confident that injectable forms are more efficacious than oral alternatives

To meet the diagnostic criteria for cvEDS, a person must meet: Major criterion 1 AND family history compatible with autosomal recessive inheritance AND at least one other major criterion OR Major criterion 1 AND family history compatible with autosomal recessive inheritance AND at least two minor criteria Major Criteria Severe progressive cardiac-valvular problems (aortic valve, mitral valve) Skin involvement: skin hyperextensibility, atrophic scars, thin skin, easy bruising Joint hypermobility (generalized or restricted to small joints) Minor criteria Inguinal hernia Pectus deformity (especially excavatum) Joint dislocations Foot deformities: pes planus, pes planovalgus, hallux valgus Classical-like EDS (clEDS) If a person meets the diagnostic criteria for clEDS, genetic testing should be done to confirm the diagnosis

Journal of Biomaterials Science, Polymer Edition , 2008