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Hypoglycemia is one of the first manifestations of metabolic reprogramming during the early phases of liver regeneration after PHx, which is likely attributable to a marked reduction in hepatic glycogen stores and gluconeogenic capacity in the metabolic stress response

In T cells of SLE patients, mTOR activation triggers ROS production, while SIRT2 concurrently upregulates IL-17A expression in these cells by modulating the mTOR complex 1 (mTORC1)/HIF-1/RORt signaling pathway, thereby contributing to the pathogenesis of SLE (101, 155)

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Adult male SD rats, weighing between 320380 g, were utilized

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