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Severe bloodbrain barrier disruption and surrounding tissue injury

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Any discussion relating to biological activity is solely in relation to published laboratory findings, including in vitro investigations, and preclinical research models not human trials

Mesenchymal Stem Cells (MSCs): Known for their neuroregenerative and immunomodulatory properties, MSCs can reduce glial inflammation, promote GABAergic neuron restoration, and enhance neuroplasticity across sleep circuits

Authors' contributions OB developed the structural design of the review, coordinated the work and did together with SJ the major part of drafting of the manuscript