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This failure supports the use of smoking cessation to control smoking

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These devices, which consist of a pen-like holder and a disposable stick, heat tobacco without burning it

While the consumption of tobacco in liquid form or as concentrated syrups is not the most common method of use throughout the Americas, there is some documentation for these practices in the Amazon and the Guianas (Wilbert Reference Wilbert1987)

A current theory proposes that nicotine has a dual response in the body